Paper Title :Correlation of Mercury, Cadmium, and Lead Levels in The Hair with Autism in Libyan Children
Author :Mohamed Abousa Gaza, Lukman Hakim, Akhmad Sabarudin, Sutiman Bambang Sumitro
Article Citation :Mohamed Abousa Gaza ,Lukman Hakim ,Akhmad Sabarudin ,Sutiman Bambang Sumitro ,
(2018 ) " Correlation of Mercury, Cadmium, and Lead Levels in The Hair with Autism in Libyan Children " ,
International Journal of Advances in Science, Engineering and Technology(IJASEAT) ,
pp. 1-9,
Volume-6, Issue-4, Spl. Iss-1
Abstract : Determination of the toxicity level of heavy metals in autism is one of the major challenges for modern scientists.
The main pathogenic factors implicated in these disorders are epigenetic changes caused by environmental factors, which
include toxic metals (Cd, Pb, Hg). In this work, hair samples from 40 Libyan children ranging from 4 to 16 years of age were
analyzed using Inductively Coupled Plasma Mass Spectrometry (ICP-MS) after microwave-assisted acid digestion (HNO3 +
H2O2) to determine the level of heavy metals (Cd, Pb and Hg) across autism and normal children. The results showed that
the mean concentrations (μg/g) of children with autism are Pb 40.99 ± 32.02, Cd 0.82 ± 0.98, and Hg 7.84 ± 10.57, while
those of normal children are Pb 37.00 ± 14.61, Cd 0.42 ± 0.27, and Hg 4.07 ± 2.54. The comparison indicated that lead (Pb),
cadmium (Cd), and mercury (Hg) contents are found higher in children with autism than those in normal children. Good
agreement with the certified values of Pb, Cd, and Hg concentrations could be achieved by the proposed method through the
analysis of the human hair certified reference of material (CRM) GBW07601
Keywords - Heavy metal, autism, hair, children, ICP-MS
Type : Research paper
Published : Volume-6, Issue-4, Spl. Iss-1
DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-14320
View Here
Copyright: © Institute of Research and Journals
|
|
| |
|
PDF |
| |
Viewed - 24 |
| |
Published on 2019-02-01 |
|