Paper Title :Multiple Homeostasis in The Insulin Receptor Reveals the Cause of Insulin Resistance in Type 2 Diabetes
Author :Yunzhang Huo, Carman Ka Man Lee, Ping Ji
Article Citation :Yunzhang Huo ,Carman Ka Man Lee ,Ping Ji ,
(2019 ) " Multiple Homeostasis in The Insulin Receptor Reveals the Cause of Insulin Resistance in Type 2 Diabetes " ,
International Journal of Advances in Science, Engineering and Technology(IJASEAT) ,
pp. 43-49,
Volume-7,Issue-3
Abstract : In regulated cells, insulin reporters are on the surface of cells. The reporters combining with the insulin lead to a
series of changes in the cells (signal transduction pathway). One of the reason that lead to Type 2 diabetes mellitus is insulin
resistance. The drugs cannot guarantee the effect because the genes themselves have a lot of steady states while the insulin can
work in some steady states but not in all steady states. When the insulin is injected, once the steady states reached by the genes
are like those resisted by the insulin, the insulin cannot work anymore. The steady states here refer to the stable steady point
with the minimum potential energy in the single cell, which may be different from the definition in biological theory. In this
paper, multiple homeostasis problems will be taken into considiration in the dynamic process, while multiple homeostasis in
the insulin receptor is proposed to reveal the cause of insulin resistance in Type 2 diabetes through the reaction dynamic
model.
Keywords - Multiple Homeostasis, Insulin Recptor Pathway, Type 2 Diabetes
Type : Research paper
Published : Volume-7,Issue-3
DOIONLINE NO - IJASEAT-IRAJ-DOIONLINE-15855
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Copyright: © Institute of Research and Journals
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Published on 2019-09-11 |
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