Paper Title :Effects of Polyphenolic Extract From Pine Bark on The Improvement of Attention Deficit/Hyperactivity Disorder in Children and Adolescent
Author :Suh-Ching Yang, Yu-Ju Su, Ying-Ru Chen, I-Cheng Lin, Yannick Piriou
Article Citation :Suh-Ching Yang ,Yu-Ju Su ,Ying-Ru Chen ,I-Cheng Lin ,Yannick Piriou ,
(2017 ) " Effects of Polyphenolic Extract From Pine Bark on The Improvement of Attention Deficit/Hyperactivity Disorder in Children and Adolescent " ,
International Journal of Management and Applied Science (IJMAS) ,
pp. 167-170,
Volume-3,Issue-3
Abstract : To examine the hypothesis that intervention with the polyphenolic complex (PE) from pine bark
improves the symptoms of ADHD and reduces oxidative stress in children and adolescent.
Methods: It was a randomized, double-blind, crossover and placebo-controlled 10-weeks period study, including two
interventional periods (4weeks/period) and one washout period (2 weeks). Data were from 8 participants with attention
deficit hyperactivity disorder (ADHD) at ages 7~16 years (seven boys and one girl). During the first interventional period,
participants were received a capsule of PE from pine bark, which contain 25mg Oligopin® per capsule, or a capsule of
placebo, which contains 25mg cellulose. Then, participants entered the washout period for 2 weeks. After 2 weeks of
washout, the participants entered the second interventional period and crossed over to receive an Oligopin® or placebo
capsule. Psychiatric examination, routine blood biochemical parameter and antioxidative status were carried out in this
study.
Results: All blood biochemical parameters were normal in the interventional periods. However, the lipid peroxidation was
significantly decreased when participants received the PE capsules. Moreover, the participants had a significant higher
accuracy and consistency during the PE interventional period.
Conclusions: The administration of the polyphenolic extract from pine bark (25 mg/day) for one month might improve the
inattention and impulsivity and reduce plasma lipid peroxidation levels in children and adolescent with ADHD.
Keywords: Polyphenolic extract from pine bark, Attention deficit/hyperactivity disorder
Type : Research paper
Published : Volume-3,Issue-3
Copyright: © Institute of Research and Journals
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Published on 2017-06-07 |
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