Paper Title :Effects of Polyphenolic Extract From Pine Bark on The Improvement of Attention Deficit/Hyperactivity Disorder in Children and Adolescent

Author :Suh-Ching Yang, Yu-Ju Su, Ying-Ru Chen, I-Cheng Lin, Yannick Piriou

Article Citation :Suh-Ching Yang ,Yu-Ju Su ,Ying-Ru Chen ,I-Cheng Lin ,Yannick Piriou , (2017 ) " Effects of Polyphenolic Extract From Pine Bark on The Improvement of Attention Deficit/Hyperactivity Disorder in Children and Adolescent " , International Journal of Management and Applied Science (IJMAS) , pp. 167-170, Volume-3,Issue-3

Abstract : To examine the hypothesis that intervention with the polyphenolic complex (PE) from pine bark improves the symptoms of ADHD and reduces oxidative stress in children and adolescent. Methods: It was a randomized, double-blind, crossover and placebo-controlled 10-weeks period study, including two interventional periods (4weeks/period) and one washout period (2 weeks). Data were from 8 participants with attention deficit hyperactivity disorder (ADHD) at ages 7~16 years (seven boys and one girl). During the first interventional period, participants were received a capsule of PE from pine bark, which contain 25mg Oligopin® per capsule, or a capsule of placebo, which contains 25mg cellulose. Then, participants entered the washout period for 2 weeks. After 2 weeks of washout, the participants entered the second interventional period and crossed over to receive an Oligopin® or placebo capsule. Psychiatric examination, routine blood biochemical parameter and antioxidative status were carried out in this study. Results: All blood biochemical parameters were normal in the interventional periods. However, the lipid peroxidation was significantly decreased when participants received the PE capsules. Moreover, the participants had a significant higher accuracy and consistency during the PE interventional period. Conclusions: The administration of the polyphenolic extract from pine bark (25 mg/day) for one month might improve the inattention and impulsivity and reduce plasma lipid peroxidation levels in children and adolescent with ADHD. Keywords: Polyphenolic extract from pine bark, Attention deficit/hyperactivity disorder

Type : Research paper

Published : Volume-3,Issue-3

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